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Prenatal alcohol exposure (PAE) is associated with a range of adverse offspring neurodevelopmental outcomes. Several studies suggest that PAE modifies DNA methylation in offspring cells and tissues, providing evidence for a potential mechanistic link to Fetal Alcohol Spectrum Disorder (FASD). This paper systematically reviewed existing evidence on the extent to which maternal alcohol use during pregnancy is associated with offspring DNA methylation.

Date:
January 2022
Journal name:
Clinical Epigenetics
Authors:
Mitchell Bestry, Martyn Symons , Alexander Larcombe, Evelyne Muggli, Jeffrey M Craig , Delyse Hutchinson, Jane Halliday, David Martino.
Page last updated 10 November 2022

The beverage alcohol industry (manufacture, marketing, distribution, and retail) is often seen as playing a role in FASD prevention strategies such as health warning labels. This paper explores the nature of the relationship between the industry and prevention programming. The study considers the place of alcohol in society; the prevalence, social and economic costs of FASD; the ethical notion of alcohol-related harm and then move onto the question of public health partnerships with the industry including the potential conflicts of interests and ethical challenges in such partnerships. Two case studies drawn from Canadian, Australian and New Zealand contexts are presented.

Date:
June 2022
Journal name:
International Journal of Environmental Research and Public Health
Authors:
Peter Choate, Dorothy Badry, Kerryn Bagley
Page last updated 31 October 2022

People with FASD encounter a range of health and allied health providers and require specialised support to ensure health services are provided safely and effectively. However, not all health professionals possess the knowledge or expertise required for the identification, assessment, referral and management of FASD. Accessible resources for understanding and managing FASD can help create awareness in health professionals and ensure patients receive the correct diagnosis and timely access to the necessary supports and services. This scoping review aims to identify and analyse FASD resources for health professionals.

Date:
September 2022
Journal name:
BMJ Open
Authors:
Josephine Chidinma Okurame, Lisa Cannon, Emily Carter, Sue Thomas, Elizabeth J Elliott, Lauren J Rice.
Page last updated 28 October 2022

As part of the Yapatjarrathati project, 47 remote health providers and community members attended a two-day workshop presenting a prototype of a culturally-safe, tiered neurodevelopmental assessment that can identify FASD in primary healthcare. Narrative analysis of the workshop transcript highlighted a collective sense of compassion for those who use alcohol to cope with intergenerational trauma, but exhaustion at the cyclical nature of FASD. There was a strong desire for a shared responsibility for First Nations children and families and a more prominent role for Aboriginal Health Workers in the assessment process. This study emphasised the benefit of continued co-design to ensure health implementation strategies match the needs of the community.

Date:
September 2022
Journal name:
International Journal of Environmental Research and Public Health
Authors:
Luke Miller, Dianne C Shanley, Marjad Page, Heidi Webster, Wei Liu, Natasha Reid, Doug Shelton, Karen West, Joan Marshall, Erinn Hawkins.
Page last updated 28 October 2022

Research has suggested that information communicated by public health and industry-funded organizations differ, as organizations linked to industry have tended to downplay risks with alcohol more broadly and pregnancy specifically. This study describes communication of health risks associated with alcohol use during pregnancy on Twitter by Australian-based organizations and stakeholders. 

Date:
October 2022
Journal name:
Substance Use and Misuse
Authors:
Lisa Schölin, Maddie Heenan.
Page last updated 28 October 2022

This study examines the effect of practice change intervention to support the implementation of guideline-recommended care for addressing alcohol use in pregnancy on self-reported alcohol use during pregnancy through a randomised, stepped-wedge controlled trial within the Hunger New England Local Health District (NSW, Australia).

Date:
August 2022
Journal name:
Substance Abuse Treatment, Prevention, and Policy
Authors:
Tracey W. Tsang, Melanie Kingsland, Emma Doherty, John Wiggers, John Attia,Luke Wolfenden, Adrian Dunlop, Belinda Tully, Ian Symonds, Chris Rissel, Christophe Lecathelinais, Elizabeth J. Elliott
Page last updated 4 October 2022

This systematic review aims to document the range and prevalence of eye abnormalities reported on children with prenatal exposure to alcohol and/ or FASD.

Date:
August 2022
Journal name:
Ophthalmic Epidemiology
Authors:
Tracey W Tsang , Amy Finlay-Jones, Kerrin Perry, John R Grigg Svetlana Popova,Melissa Mei Yin Cheung, Carol Bower, Patrick Tam, Robyn V Jamieson, and Elizabeth J Elliott.
Page last updated 4 October 2022

This study aimed to examine health-related variables in a cohort of expectant fathers to identify potential focus areas for interventions designed to optimise health and wellbeing outcomes. 498 partners of pregnant women who accessed antenatal services at a large maternity unit in a Western Australian hospital were recruited as part of the ORIGINS Project.

Date:
March 2022
Journal name:
Parenting and Family
Authors:
Simone Pettigrew, Michelle I. Jongenelis, Sophie Cronin, Liyuwork M. Dana, Desiree Silva, Susan L. Prescott, Bu B. Yeap
Page last updated 9 August 2022

This comprehensive clinical paediatric assessment examines 103 young people sentenced to detention in Western Australia (WA) and participating in the first Fetal Alcohol Spectrum Disorder (FASD) prevalence study. The findings of multiple and serious impairments and health issues, through completion of comprehensive clinical paediatric and multidisciplinary health and neuro-developmental assessments for this study, support their routine provision to all young people on entry to systems of juvenile justice.

Date:
July 2022
Journal name:
Journal of Fetal Alcohol Spectrum Disorder
Authors:
Raewyn Mutch, Jacinta Freeman, Natalie Kippin, Bernadette Safe, Carmela Pestell, Hayley Passmore, Sharynne Hamilton, Helen shield, Emma Argiro, Candace Rainsford, Carmen Condon, Roslyn Giglia, Rochelle Watkins, Rhonda Marriot, Carol Bower
Page last updated 9 August 2022

Prenatal alcohol exposure can contribute to long term adverse health outcomes. Development of the skeletal system begins at the early embryonic stage and continues into early adulthood but the effect of prenatal alcohol exposure on skeletal growth is relatively unexplored in a clinical population. This study examines bone, fat, and muscle accrual in children and adolescents diagnosed with, or at risk of, fetal alcohol spectrum disorders (FASDs). By adolescence, those with FASD were shorter and had lower areal bone mineral density and lean tissue mass than typically developing peers. Overall, adolescents diagnosed with FASDs had greater odds of impairments to bone and body composition.

Date:
August 2022
Journal name:
Bone
Authors:
Sophia L. Young, Linda A. Gallo, Denise S.K. Brookes, Nicole Hayes, Maree Maloney, Karen Liddle, Amanda James, Karen M. Moritz, Natasha Reid
Page last updated 9 August 2022